Integrated Analysis of Multiple Microarray Studies to Identify Core Gene-Expression Signatures Involved in Tubulointerstitial Injury in Diabetic Nephropathy

<div>The heat map of hub genes selected by WGCNA and PPI network visualization of the coexpressed module. (a) The heat map of hub genes in the green module by WGCNA; (b) the heat map of hub genes in the blue module by WGCNA; (c) PPI network of all the genes in the green module based on STRING database; (d) PPI network of genes identified by calculating the top 30 nodes with neighbors and expanded ranked by degree method in “cyto-hubba,” a plug-in of Cytoscape software. Red: upregulation; blue: downregulation.</div>

BioMed Research International

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Figure 4

Figure 4: Integrated Analysis of Multiple Microarray Studies to Identify Core Gene-Expression Signatures Involved in Tubulointerstitial Injury in Diabetic Nephropathy 

Figure 4 | Integrated Analysis of Multiple Microarray Studies to Identify Core Gene-Expression Signatures Involved in Tubulointerstitial Injury in Diabetic Nephropathy 