Antioxidant and Anticarcinogenic Potentials of Propolis for Dimethylhydrazine-Induced Colorectal Cancer in Wistar Rats

Figure 4

Comparison of colon tissue indices of the different groups. Normal tissue presents in the control, EEP, and vitamin E groups. ACF (aberrant crypt foci) with dysplasia is shown with the left arrow. The epithelium displays nuclear stratification with rounded nuclei and hyperchromatic nucleoli. There is marked depletion of goblet cells in the dysplastic crypts. Necrosis (right arrow), mitosis (up arrow), and inflammatory cells infiltration (stars) are observed in DMH and therapeutic groups. Magnification 10× and 40×, H&E stain.