Research Article

Optimizing the Extraction Conditions of Hydroxytyrosol from Olive Leaves Using a Modified Spherical Activated Carbon: A New Experimental Design

Table 7

Analysis of variance of the quadratic model in Box-Behnken design.

SourceSum of squaresdfMean square-value-value

Model3201,449355,7270,33< 0.0001Significant
A (adsorbent ratio)1755,5811755,58347,10< 0.0001
B (temperature)34,24134,246,770,0481
C (time)741,511741,51146,60< 0.0001
AB9,0019,001,780,2398
AC106,611106,6121,080,0059
BC4,8214,820,95260,3739
339,401339,4067,100,0004
67,09167,0913,260,0149
214,391214,3942,390,0013
Residual25,2955,06
Lack of fit25,2938,43
Pure error0,000020,0000
Cor Total3226,7314