Hirudin Regulates Vascular Function in Chronic Renal Failure through Modulating Macrophage Polarization

Figure 2

Hiru modulates vascular injury and macrophage M1/M2 polarization in CRF rat models. (a) The endothelial injury and vascular smooth muscle hyperplasia were measured by H&E staining. IHC assay was to detect (b) iNOS and (c) Arg-1 expression in rat vascular tissues. Scale bar, 50 μm.

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(b)

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