Differential Effect of Vaginal Microbiota on Spontaneous Preterm Birth among Chinese Pregnant Women
Table 2
The associations between vaginal taxa and sPTB in the GDM and non-GDM groups.
Vaginal taxa (P/A)
Non-GDM ()
GDM ()
cOR (95% CI)
aOR (95% CI)a
cOR (95% CI)
aOR (95% CI)a
p_Proteobacteria
2.85 (1.36-5.96)
0.006
3.39 (1.55-7.39)
0.002
0.46 (0.09-2.41)
0.359
0.65 (0.09-4.48)
0.659
g_Streptococcus
3.76 (1.80-7.85)
0.0004
3.58 (1.68-7.65)
0.001
0.94 (0.15-6.01)
0.952
1.30 (0.16-10.45)
0.802
s_L.para.gasseri
2.66 (1.12-6.34)
0.027
3.12 (1.24-7.84)
0.016
0.32 (0.06-1.70)
0.181
0.30 (0.05-1.87)
0.197
s_L.mulieris
0.49 (0.24-1.02)
0.057
0.54 (0.26-1.13)
0.101
0.65 (0.13-3.40)
0.614
0.42 (0.07-2.61)
0.354
aThe association between vaginal taxa and sPTB was estimated with logistic model adjusted for age, number of previous pregnancies, prepregnancy body mass index, and passive smoking. aOR: adjusted odds ratio; CI: confidence interval; cOR: crude odds ratio; GDM: gestational diabetes mellitus; P/A: presence/absence.