Research Article

Differential Effect of Vaginal Microbiota on Spontaneous Preterm Birth among Chinese Pregnant Women

Table 2

The associations between vaginal taxa and sPTB in the GDM and non-GDM groups.

Vaginal taxa (P/A)Non-GDM ()GDM ()
cOR (95% CI)aOR (95% CI)acOR (95% CI)aOR (95% CI)a

p_Proteobacteria2.85 (1.36-5.96)0.0063.39 (1.55-7.39)0.0020.46 (0.09-2.41)0.3590.65 (0.09-4.48)0.659
g_Streptococcus3.76 (1.80-7.85)0.00043.58 (1.68-7.65)0.0010.94 (0.15-6.01)0.9521.30 (0.16-10.45)0.802
s_L.para.gasseri2.66 (1.12-6.34)0.0273.12 (1.24-7.84)0.0160.32 (0.06-1.70)0.1810.30 (0.05-1.87)0.197
s_L.mulieris0.49 (0.24-1.02)0.0570.54 (0.26-1.13)0.1010.65 (0.13-3.40)0.6140.42 (0.07-2.61)0.354

aThe association between vaginal taxa and sPTB was estimated with logistic model adjusted for age, number of previous pregnancies, prepregnancy body mass index, and passive smoking. aOR: adjusted odds ratio; CI: confidence interval; cOR: crude odds ratio; GDM: gestational diabetes mellitus; P/A: presence/absence.