Computer Image Analysis Reveals C-Myc as a Potential Biomarker for Discriminating between Keratoacanthoma and Cutaneous Squamous Cell Carcinoma

Table 2

C-Myc staining patterns in Keratoacanthoma (KA) and Cutaneous Squamous Cell Carcinoma (cSCC) patients.

	KA ( (%))	cSCC ( (%))	value
Diffuse staining pattern	5 (11.90)	21 (67.74)	0.000
Peripheral staining pattern	37 (88.10)	10 (32.26)

Note. (1) Diffuse staining pattern: C-Myc expression was mainly located in the nuclei and/or in the cytosol of most cells. (2) Peripheral staining pattern: C-Myc expression was mainly located in the nuclei of basal lamina cells at the initial portion of tumor infiltration and/or showed positive staining within the nuclei of basal lamina tumor cells and some spiny lamina cells.