Prevalence of Epstein–Barr Virus Infection and Mismatch Repair Protein Deficiency and the Correlation of Immune Markers in Tibetan Patients with Gastric Cancer
Table 2
Correlations between the EBER status and immune microenvironment markers in Tibetan patients with gastric cancer.
Variable
Category
EBV-negative ()
EBV-positive ()
value (Fisher’s exact test)
Stromal CD3
High
51 (46.8%)
9 (81.8%)
0.017
Low
58 (53.2%)
1 (9.1%)
Intraepithelial CD3
High
52 (47.7%)
9 (81.8%)
0.017
Low
57 (52.3%)
1 (9.1%)
Total CD3_all
High
51 (46.8%)
9 (81.8%)
0.017
Low
58 (53.2%)
1 (9.1%)
Stromal CD8
High
51 (46.8%)
9 (81.8%)
0.053
Low
58 (53.2%)
2 (18.2%)
Intraepithelial CD8
High
49 (45.0%)
11 (100%)
0.001
Low
60 (55.0%)
0 (0%)
Total CD8
High
50 (45.9%)
10 (90.9%)
0.008
Low
59 (54.1%)
1 (9.1%)
PD-L1 expression#
CPS≥1%
31 (28.4%)
8 (72.7%)
0.005
CPS<1%
75 (68.8%)
3 (27.3%)
Note: CD3 expression in 1 patient could not be evaluated; #PD-L1 expression in 3 patients could not be evaluated.
