INSM1 Expression in Mesenchymal Tumors and Its Clinicopathological Significance

Figure 8

Positive expression of INSM1 in liposarcoma. (a, d) Highly differentiated liposarcoma: there are scattered hyperchromatic heteromorphic cells in the fibrous collagen stroma, marked fibrous septa, hyperchromatic nuclei, and enlarged spindle cells. INSM1 staining was positive in the tumor region. Tumor cells were scattered in the mucus matrix. (b, e) Dedifferentiated liposarcoma: the cells are disordered, some of them are fasciculate/lumpy, and the nuclei of tumor cells are hyperchromatic. (c, f) Myxoid liposarcoma: tumor cells are seen scattered along a curvilinear network of thin-walled blood vessels in the mucinous matrix (200x).

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