Associations between Gene-Gene Interaction and Overweight/Obesity of 12-Month-Old Chinese Infants

Table 4

Cumulative effect of the risk SNPs between case and control groups.

Number of risk genotypes	Case group; (%)	Control group; (%)	OR (95% CI)
0	11 (5.98)	71 (15.96)	1	—
1	59 (32.07)	172 (38.65)	2.15 (1.06, 4.38)	0.60
2	58 (31.52)	119 (26.74)	3.19 (1.55, 6.56)	0.04
≥3	56 (30.43)	83 (18.65)	4.30 (2.07, 8.96)	<0.01
Linear-by-linear regression analysis

Notes: ORs of number of risk genotypes were calculated by unconditional multivariable logistic regression analysis, adjusting for child gender, BMI_Z at birth, feeding pattern in the 1-month old, weight gain velocity from birth to 3-month old, gestational weight gain, and parental BMI;P from unconditional multivariable logistic regression analysis;^#P from linear-by-linear regression anlaysis.