Research Article

Associations between Gene-Gene Interaction and Overweight/Obesity of 12-Month-Old Chinese Infants

Table 1

General characteristics of participants in case and control groups.

Case group ()Control group ()

Infants
 Boys, (%)92 (42.01)284 (55.15)0.0011
 BMI_Z at birth-0.52 (1.18)-0.46 (1.15)0.5528
 BMI_Z at 12-month old1.64 (1.31, 2.00)0.03 (-0.53, 0.50)<.0001
 Feeding pattern in the 1-month old, (%)0.1330
  Exclusive breastfeeding87 (39.73)240 (46.60)
  Mixed feeding106 (48.40)232 (45.05)
  Formula feeding26 (11.87)43 (8.35)
 Weight gain velocity (0-3 months old)0.63 (-0.07, 1.56)0.45 (-0.36, 1.18)0.0028
Mothers
 Age (year)28.82 (26.97, 31.47)28.44 (26.50, 31.00)0.1430
 Educational level, (%)0.6459
  Middle school or under10 (5.46)32 (7.24)
  High school/technical33 (18.03)82 (18.55)
  University/college128 (69.95)290 (65.61)
  Master’s degree or advanced12 (6.56)38 (8.60)
 Prepregnancy smoking, (%)2 (0.92)19 (3.73)0.0378
 Prepregnancy BMI (kg/m2)20.45 (18.82, 22.55)20.00 (18.25, 21.99)0.0209
 Gestational weight gain (kg)14.10 (11.76, 17.00)14.40 (12.00, 17.00)0.7177
 Gestational week (week)39.29 (38.57, 40.00)39.29 (38.43, 40.14)0.8229
 Caesarean section, (%)85 (38.81)184 (35.73)0.4275
Fathers
 Educational level, (%)0.5527
  Middle school or under11 (6.04)24 (5.52)
  High school/technical21 (11.54)68 (15.63)
  University/college133 (73.08)310 (71.26)
  Master’s degree or advanced17 (9.34)33 (7.59)
 BMI (kg/m2)23.66 (21.72, 26.23)23.82 (21.63, 25.65)0.6166
 Smoking, (%)57 (27.54)143 (28.83)0.7288
Household monthly income (yuan/RMB), (%)0.9618
  <500198 (44.75)197 (38.25)
 5001~800026 (11.87)126 (24.47)
 8001~1500066 (30.14)128 (24.85)
  >1500029 (13.24)64 (12.43)

Note: refers to significant difference between the groups, ; results from variables with normal distribution were presented as mean (standard deviation), with skewed distribution that were present as median (interquartile range), results from category variables were presented as frequency (percentage).