Plasma-Derived Exosomal hsa-miR-4488 and hsa-miR-1228-5p: Novel Biomarkers for Dermatomyositis-Associated Interstitial Lung Disease with Anti-Melanoma Differentiation-Associated Protein 5 Antibody-Positive Subset

<div>Top 10 Gene Ontology terms in the categories of (a) biological process, (b) cellular component, and (c) molecular function regulated by candidate target genes of significantly differentially expressed microRNAs in plasma exosomes. HC: healthy controls; DM-ILD-MDA5 Ab(+): DM patients with ILDs and anti-melanoma differentiation-associated protein 5 antibody-positive status; DM-nonILD-MSA16(-): DM patients without ILDs who were negative for 16 detectable myositis-specific antibodies; ILD: interstitial lung disease; DM: dermatomyositis.</div>

BioMed Research International

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Figure 5

Figure 5: Plasma-Derived Exosomal hsa-miR-4488 and hsa-miR-1228-5p: Novel Biomarkers for Dermatomyositis-Associated Interstitial Lung Disease with Anti-Melanoma Differentiation-Associated Protein 5 Antibody-Positive Subset 

Figure 5 | Plasma-Derived Exosomal hsa-miR-4488 and hsa-miR-1228-5p: Novel Biomarkers for Dermatomyositis-Associated Interstitial Lung Disease with Anti-Melanoma Differentiation-Associated Protein 5 Antibody-Positive Subset 