Research Article

[Retracted] High-Throughput Screen of Natural Compounds and Biomarkers for NSCLC Treatment by Differential Expression and Weighted Gene Coexpression Network Analysis (WGCNA)

Table 4

The regulated results of the common genes.

PathwayCommon genes in medicineRegulate

MAPK signaling pathwayIL1R1Downregulated
DUSP4Upregulated
EGFRUpregulated in B. fruticosa and A. pierreana, downregulated in S. scandens
EREGUpregulated in B. fruticosa and A. pierreana, downregulated in S. scandens
MAP3K20Upregulated in B. fruticosa and A. pierreana, downregulated in S. scandens

NF-kappa B signaling pathwayIL1R1Downregulated
BIRC3Upregulated
TRIM25Upregulated
TAB3Upregulated
PLAUUpregulated
IL1BUpregulated

p53 signaling pathwayMDM2Upregulated
CDKN1AUpregulated

TGF-beta signaling pathwayID2Downregulated
ID1Upregulated in A. pierreana, downregulated in others
ID4Downregulated