(a) Percentage of new bone formation |
| | The discarding study | WMD (95% CI) | Heterogeneity (, %) |
| | Thor et al. 2007 [21] | 1.87 (-2.14, 5.89) | 71 | | Cömert Kılıç et al. 2017 (PRF) [17] | 3.44 (-1.09, 7.96) | 79 | | Cömert 2017 (PRP) [17] | 3.12 (-1.34, 7.58) | 79 | | Ebru 2018 | 3.60 (-1.54, 8.74) | 75 | | Kassolis and Reynolds 2005 [24] | 2.57 (-1.84,6.99) | 78 | | Khairyet al. 2013 [19] | 4.48 (-1.84,8.35) | 71 | | Nizam 2017 | 3.38 (-1.38,8.14) | 79 | | Pichotano et al. 2019 [14] | 1.85 (-2.13,5.83) | 73 | | Taschieri et al. 2016 [18] | 2.56 (-1.78,6.89) | 78 | | Zhang et al. 2012 [20] | 2.69 (-1.85,7.23) | 78 |
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(b) Percentage of residual bone substitute material |
| | The discarding study | WMD (95% CI) | Heterogeneity (, %) |
| | Cömert Kılıç et al. (PRF) [17] | -6.56 (-12.49, -0.63) | 63 | | Cömert Kılıç et al. (PRP) [17] | -5.93 (-12.42, 0.57) | 69 | | Kassolis and Reynolds 2005 [24] | -3.48 (-8.68, 1.72) | 56 | | Nizam 2017 | -6.53 (-12.78, -0.31) | 59 | | Pichotano et al. 2019 [14] | -3.71 (-9.57, 2.15) | 56 | | Zhang et al. 2012 [20] | -4.55 (-10.66,1.55) | 69 |
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(c) The Implant stability quotient values |
| | The discarding study | SMD (95% CI) | Heterogeneity (, %) |
| | Ebru 2018 | -0.84 (-2.63, 0.95) | 88 | | Pichotano et al. 2019 [14] (implant loading) | -0.77 (-2.74, 1.20) | 88 | | Pichotano et al. 2019 [14] (implant immediately) | 0.13 (-0.48, 0.74) | 0 |
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(d) The bone density by radiological analysis |
| | The discarding study | SMD (95% CI) | Heterogeneity (, %) |
| | Consolo et al. 2007 [22] | -0.67 (-1.60, 0.27) | 50 | | Ebru 2018 | 1.92 (-1.88, 5.71) | 96 | | Khairy et al. 2013 [19] | 1.42 (-2.80, 5.63) | 96 | | Raghoebar et al. 2005 [23] | 1.75 (-2.03, 5.53) | 96 |
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