Review Article

Selenium Level in Patients with Vitiligo: A Meta-Analysis

Table 1

Characteristics of the 8 studies included for meta-analysis.

Study/yearCountrySkin typeSampleAge, (range)Vitiligo/controlType/stageCaseControlUni/methodsNOS score

Teherani and Nagy-Vezekenyi [24]AustriaNABlood(9-16)5/810-25% body surfaceμg/g dry weight neutron activation analysis4
Tu et al. [26]ChinaNASerum29.1 (18-51)29/37Localized 13
Segmental 5
Generalized 11
μg/L fluorescence spectrophotometry7
Beazley et al. [19]GermanyII (n.5)
III (n.53)
IV (n.3)
Serum38.9 ()61/5932Vulgaris 44
Acrofacial 13
Segmental 2
Focal form 1
Totalis 1
(2 active stages)
μmol/L atomic absorption spectrophotometry6
Kang et al. [27]ChinaDark-skinned patientsSerum(3-64)30/343 m-30 ymg/L5
Ozturk et al. [25]TurkeyNAPlasma (16-43)30/30Generalized
Stable
Ppb fluorescence spectrophotometer7
Barikbin et al. [17]IranIII or IVSerum31.8 (9-82)60/45Vulgarisμmol/L flameless atomic absorption method6
Zhao et al. [28]ChinaIISerum(3-65)36/16Active 18/stable 18
Localized 16
Generalized 17
Scattered 2
Segmental 1
ng/L6
Wacewicz et al. [18]PolandNASerum (21-73)Generalizedμg/L electrothermal atomic absorption spectrometry method7