Association between Renal Podocalyxin Expression and Renal Dysfunction in Patients with Diabetic Nephropathy: A Single-Center, Retrospective Case-Control Study

Table 1

Baseline clinical characteristics of the patients with diabetic nephropathy at the time of renal biopsy.

	High expression group ()	Low expression group ()	value
Age (years)			0.401
Male/female	9/9	8/6	0.735
Course of diabetes (months)	50.5 (30.5-72.8)	78 (47.7-95.5)	0.035
Course or nephropathy (months)			0.395
Mean arterial pressure (mmHg)			0.454
HbA1c (%)			<0.001
FPG (mmol/L)			0.456
Triglycerides (mmol/L)			0.66
Cholesterol (mmol/L)			0.914
Albumin (g/L)			0.001
Urinary NAG (U/L)			0.462
Urinary protein (g/24 h)			0.006
Serum creatinine (μmol/L)			<0.001
eGFR			0.001
Urinary PCX/UCr			<0.001
ACE-i or ARB	18 (100.0)	14 (100.0)	>0.99

eGFR: estimated glomerular filtration rate; FPG: fasting plasma glucose; HbA1c: glycated hemoglobin; NAG: N-acetyl-beta-D-glucosaminidase; PCX: podocalyxin; UCr: urinary creatinine; ACE-i: angiotensin-converting enzyme inhibitor; ARB: angiotensin receptor blocker.