Identification of Key Genes of Human Advanced Diabetic Nephropathy Independent of Proteinuria by Transcriptome Analysis

Figure 5

Correlation between eGFR and mRNA expression of hub genes in tubulointerstitium. (a–f) The expression of upregulated genes relating to inflammation or fibrosis negatively correlated with eGFR. (g–l) The expression of downregulated genes regulating lipid metabolism and oxidative processes positively correlated with eGFR. eGFR: estimated glomerular filtration rate.

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