Let-7c-5p Is Involved in Chronic Kidney Disease by Targeting TGF-β Signaling

Table 1

Summary of demographics and clinical characteristics of donors.

Variables	Group		p value
	CKD	NC
	()	()
Gender
Male, (%)	16 (69.6%)	10 (50.0%)
Female, (%)	7 (30.4%)	10 (50.0%)
Age (year)			0.001
Creatinine (μmol/L)			0.021
eGFR (mL/min per 1.73 m^2)			0.348
Cystatin C (mg/L)			0.005
Carbamide (mmol/L)			0.028
Urinary protein levels
+, (%)	4 (17.4%)
++, (%)	7 (30.4%)
+++, (%)	6 (26.1%)
++++, (%)	6 (26.1%)
Hemoglobin (g/L)			0.01
Albumin (g/L)			<0.001
Classification of CKD
G1, (%)	11 (47.8%)
G2, (%)	4 (17.4%)
G3a, (%)	6 (26.1%)
G3b, (%)	1 (4.3%)
G4, (%)	1 (4.3%)
G5, (%)	0 (0%)

Data are expressed as numbers with percentages in parentheses or as . Classification of CKD, according to international guidelines. G1: eGFR≥90 mL/min per 1.73 m², G2: 60 mL/min per 1.73 m² ≤ eGFR≤89 mL/min per 1.73 m², G3a: 45 mL/min per 1.73 m² ≤ eGFR≤59 mL/min per 1.73 m², G3b: 30 mL/min per 1.73 m² ≤ eGFR≤44 mL/min per 1.73 m², G4: 15 mL/min per 1.73 m² ≤ eGFR≤29 mL/min per 1.73 m², G5: eGFR<15 mL/min per 1.73 m² [21].