Research Article

Let-7c-5p Is Involved in Chronic Kidney Disease by Targeting TGF-β Signaling

Figure 4

Correlation between hsa-let-7c-5p expression and clinicopathological factors of patients with CKD. (a) Serum creatinine levels are negatively correlated with relative hsa-let-7c-5p expression levels. (b) Serum creatinine levels are positively correlated with relative TGF-β1 expression. (c) hsa-let-7c-5p expression levels show a positive correlation with CKD patient eGFR. (d) Patients with proteinuria (4+) have significantly decreased hsa-let-7c-5p levels, in comparison with patients with proteinuria (+) and proteinuria (2+). (e) Significant decrease in hsa-let-7c-5p levels of stage 3-4 CKD patients, compared with that of early-stage patients. . Bar results are expressed as .
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