miR-1929-3p Overexpression Alleviates Murine Cytomegalovirus-Induced Hypertensive Myocardial Remodeling by Suppressing Ednra/NLRP3 Inflammasome Activation

Figure 6

miR-1929-3p overexpression suppressed MCMV-induced expression of the NLRP3 inflammasome and secretion of IL-1β in the myocardium after MCMV infection. (a) Western blotting analysis of NLRP3, ASC, pro-caspase-1, caspase-1, pro-IL-1β, IL-1β, and IL-18 protein. (b–j) Densitometric analysis of (a). The data are expressed as the (), vs. the age-matched control groups. , the MCMV+miR-1929-3p groups vs. the age-matched MCMV groups.

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