miR-1929-3p Overexpression Alleviates Murine Cytomegalovirus-Induced Hypertensive Myocardial Remodeling by Suppressing Ednra/NLRP3 Inflammasome Activation

<div>miR-1929-3p overexpression downregulated Ednra and alleviated MCMV-induced cardiac dysfunction. (a) Western blotting analysis of Ednra protein. (b) Densitometric analysis of (a). (c) qRT-PCR analysis of Ednra mRNA. The value was normalized to the control groups, which was set to 1. (d) Images of the M-mode of LV. (e–i) LVPWd, LVIDs, LVIDd, EF%, and FS%. 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LVPWd: left ventricular end-diastolic posterior wall dimension; LVIDs: left ventricular end-systolic diameter; LVIDd: left ventricular end-diastolic diameter; EF%: ejection fraction; FS%: fractional shortening.</div>

BioMed Research International

fig4

Figure 4

Figure 4: miR-1929-3p Overexpression Alleviates Murine Cytomegalovirus-Induced Hypertensive Myocardial Remodeling by Suppressing Ednra/NLRP3 Inflammasome Activation 

Figure 4 | miR-1929-3p Overexpression Alleviates Murine Cytomegalovirus-Induced Hypertensive Myocardial Remodeling by Suppressing Ednra/NLRP3 Inflammasome Activation 