Autophagy Suppresses Toll-Like Receptor 3-Mediated Inflammatory Reaction in Human Epidermal Keratinocytes

Figure 1

(a) Skin specimens were obtained from normal and psoriatic lesions, and immunohistochemistry was performed using the anti-light chain 3 (LC3) antibody. The LC3 level in psoriatic lesions was higher than that of normal epidermis. (b) BALB/c mice were topically applied with imiquimod cream. The LC3 level in imiquimod-treated epidermis was markedly increased compared to control epidermis.

(a)

(b)