Overexpression of Sphingosine Kinase-1 and Sphingosine-1-Phosphate Receptor-3 in Severe Plasmodium falciparum Malaria with Pulmonary Edema

Figure 3

Correlations between the SphK-1 and S1PR-3 expression levels in the lungs of patients with severe P. falciparum and PE were assessed by using Spearman’s rank correlation test. Positive correlations were found between the SphK-1 and S1PR-3 expression levels in (a) pulmonary ECs, (b) alveolar epithelial cells, and (c) AMs.

(a)

(b)

(c)