Predicting Factors for Rapid Progressive Chronic Kidney Disease in Primary Glomerular Disease Patients with Moderate-to-Severe Stage

Table 2

Laboratory and imaging characteristics of the study population at baseline.

Indicators		Group NR ()	Group R ()
Renal function	Baseline eGFR (mL/min·1.73 m^2)	31.05 (16.01, 41.18)	23.35 (17.40, 41.64)	0.80
	ΔeGFR (mL/min·1.73 m2)	1.466 (-4.738, 4.646)	15.302 (8.824, 22.694)	0.000
	CysC (mg/L)			0.17
	UA (mmol/L)			0.60
Blood routine, urine routine	WBC (10^12/L)			0.86
	Hb (g/L)			0.014
	Hct (%)			0.020
	uSG	1.02 (1.015, 1.02)	1.02 (1.015, 1.02)	0.80
	uPH	5.5 (5.0, 6.0)	6 (5.38, 6.50)	0.62
Lipid	TC (mmol/L)	5.21 (4.06, 6.41)	4.40 (3.83, 5.56)	0.19
	TG (mmol/L)	1.71 (1.0, 2.66)	1.63 (1.28, 2.57)	0.74
	LDL-C (mmol/L)	2.64 (2.06, 3.37)	2.28 (1.97, 2.82)	0.37
	HDL-C (mmol/L)	1.28 (0.97, 1.62)	1.2 (0.90, 1.37)	0.024
Electrolyte	K (mmol/L)			0.43
	Na (mmol/L)			0.98
	Cl (mmol/L)			0.44
	CO2CP (mmol/L)			0.83
	Ca (mmol/L)			0.99
	IP (mmol/L)			0.09
Nutrition index	Alb (g/L)	36.9 (32.95, 41.68)	34.55 (30.50, 38.08)	0.28
	Fe (umol/L)			0.28
	Transferrin (g/L)			0.13
	PA (g/L)			0.22
Inflammatory index	CP (mg/L)			0.91
	ESR (mm/hr)	31 (21, 57)	58.50 (30.50, 73.50)	0.06
	CRP (mg/L)	1.9 (0.4, 7.36)	1.40 (0.70, 5.18)	0.71
Glomerular function	sα1-MG (mg/L)			0.87
	sβ2-MG (mg/L)			0.021
	sRBP (mg/L)			0.50
	BF (mg/L)			0.21
	Hcy (umol/L)	19.65 (11.75, 24.58)	17.60 (9.75, 26.40)	0.16
	sNAG (U/L)			0.77
Renal tubular function	uβ2-MG (μg/mL)	0.63 (0.15, 4.43)	2.20 (1.06, 4.44)	0.52
	umicroAlb (mg/L)	264.1 (85.6, 631.5)	267.20 (138.15, 572.25)	0.89
	uα1-MG (μg/mL)	14.45 (8.55, 24.88)	19.80 (9.15, 39.70)	0.033
	uRBP (mg/L)	6.13 (1.87, 9.48)	6.99 (2.97, 13.00)	0.49
	uNAG (U/L)	9.4 (5.1, 17.75)	8.50 (4.75, 19.20)	0.79
uACR (mg/L)		39.34 (8.63, 106.67)	80.73 (19.25, 154.36)	0.036
Kidney size (cm^3/m^2)				0.035
Renal parenchyma	I	3 (4.3%)	2 (4.8%)	0.037
	II	25 (35.7%)	8 (19%)
	III	7 (10%)	6 (14.3%)
	IV	35 (50%)	26 (61.9%)
CTR				0.049

Alb: albumin; BF: B factor; Ca: Calcium; Cl: chlorine; CO2CP: carbon dioxide binding force; CP: Copper blue protein; CTR: cardiothoracic ratio; CysC: cystatin C; eGFR: estimated glomerular filtration rate; Hb: hemoglobin; Hct: hematocrit; Hcy: homocysteine; HDL-C: high-density lipoprotein cholesterol; IP: phosphorus; K: potassium; LDL-C: low-density lipoprotein cholesterol; Na: sodium; PA: prealbumin; S α1-MG: blood α1 microglobulin; S β2-MG: blood β2 microglobulin; SRBP: Schromatol protein; TC: total cholesterol ester; TG: total triglycerides; UA: uric acid; UACR: ratio of urinary albumin creatinine; umicroAlb: urinary microalbumin; USG: urine gravity; Uα1-MG: urine α1 microglobulin; Uβ2-MG: urine β2 microglobulin; WBC: white blood cell count.