Research Article
Negative Regulation of Tec Kinase Alleviates LPS-Induced Acute Kidney Injury in Mice via theTLR4/NF-κB Signaling Pathway
Figure 4
LFM-A13 inhibited Tec protein expression in LPS-induced AKI. (a) Representative immunohistochemical staining showed renal Tec protein staining in the control, LPS group, and different concentration of LFM-A13 (40, 60, and 80 mg/kg) prior to LPS injection. Boxed areas in the cortical and medullar regions are enlarged. Arrowheads indicate renal tubules. . (b) Expression of Tec kinase in whole kidney lysates was detected by Western blot. (c) Quantitative analysis of Tec protein was determined by integral optical density (, ).
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