Different Numbers of Long-Pulse 1064-nm Nd-YAG Laser Treatments for Onychomycosis: A Pilot Study

Table 5

Univariable and multivariable logistic regression analysis for efficacy rate at 24 weeks.

Variable	Univariable logistic regression		Multivariable logistic regression
	OR (95%CI)		OR (95%CI)
Treatment group
Group A	Reference
Group B	1.314 (0.845, 2.043)	0.225	1.009 (0.564, 1.805)	0.976
Group C	2.074 (1.265, 3.401)	0.004	2.589 (1.342, 4.994)	0.005
Age (years)	0.919 (0.896, 0.941)	<0.001	0.900 (0.870, 0.931)	<0.001
Duration of disease (years)	0.789 (0.671, 0.927)	0.004	1.114 (0.883, 1.406)	0.363
Gender
Male	Reference
Female	1.320 (0.882, 1.974)	0.177
Nail thickness (mm)
<1	Reference
1–2	0.075 (0.030, 0.191)	<0.001	0.24 (0.079, 0.734)	0.012
Mean laser energy (J/cm^2)	0.979 (0.967, 0.992)	0.001	0.998 (0.981, 1.015)	0.836
Location of infected nails
Fingernail	Reference
Toenail	1.285 (0.765, 2.157)	0.343
Severity of infected nails
II	Reference
III	0.108 (0.070, 0.168)	<0.001	0.107 (0.052, 0.219)	<0.001
Clinical type of onychomycosis		<0.001		0.734
DLSO	Reference
WSO	0.644 (0.348, 1.190)	0.160	0.968 (0.441, 2.127)	0.936
PSO	0.187 (0.053, 0.659)	0.009	0.575 (0.124, 2.674)	0.480
TDO	0.367 (0.217, 0.621)	<0.001	1.304 (0.576, 2.955)	0.525

Group A: four sessions; Group B: eight sessions; Group C: 12 sessions. OR: odds ratio; CI: confidence interval; DLSO: distal lateral subnail onychomycosis; WSO: white superficial onychomycosis; PSO: proximal subnail onychomycosis; TDO: total dystrophy onychomycosis.