Different Numbers of Long-Pulse 1064-nm Nd-YAG Laser Treatments for Onychomycosis: A Pilot Study

Table 4

Efficacy rates according to severity of onychomycosis in each group at different time points.

Group	Cases,	Efficacy rate, (%)
		Week 8	Week 16	Week 24
Group A
II	75	47 (62.7%)	53 (70.7%)	54 (72.0%)
III	80	8 (10.0%)	7 (8.8%)	4 (5.0%)
		<0.001	<0.001	<0.001
Group B
II	88	46 (52.3%)	62 (70.5%)	58 (65.9%)
III	87	9 (10.3%)	11 (12.6%)	19 (21.8%)
		<0.001	<0.001	<0.001
Group C
II	57	28 (49.1%)	37 (64.9%)	41 (71.9%)
III	55	3 (5.5%)	19 (34.6%)	21 (38.2%)
		<0.001	0.001	<0.001

Group A: four sessions; Group B: eight sessions; Group C: 12 sessions. The clinical efficacy rate was defined as the total percentage of nails with complete response and significant response. “Complete response or cure” was defined as fully normal appearing nail measured from the proximal nail fold to involved nail; “significant response” was defined as >60% normal-appearing nail compared with the area of the initially infected nail; “moderate response” was defined as 20–60% normal-appearing nail; and “no response” was defined as <20% normal-appearing nail.