Research Article
Isorhamnetin Induces Melanoma Cell Apoptosis via the PI3K/Akt and NF-κB Pathways
Figure 6
Effect of PFKFB4 on isorhamnetin-induced PI3K/Akt pathway inhibition. (a, b) When treated with IH (100 μmol/L), the PFKFB4 expression level was significantly decreased. (c, d) PFKFB4 expression was downregulated after treatment with specific siRNA. (e, f) Effect of PFKFB4 on the PI3K/Akt pathway in IH-treated B16F10 cells. Each experiment was repeated at least three times. compared with control; compared with control; compared with control.
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