Relationship between Endplate Defects, Modic Change, Disc Degeneration, and Facet Joint Degeneration in Patients with Low Back Pain

Table 1

Types of MC in the lumbar vertebral body according to MRI.

Modic classification: MRI changes and associated pathological features
Vertebral endplates	T1-weighted sequences	T2-weighted sequences	Histopathology
Modic 1	Hypo-signal	Hyper-signal	Oedema, inflammation
Modic 2	Hyper-signal	Iso-signal or hyper-signal	Fatty changes
Modic 3	Hypo-signal	Hypo-signal	Fibrous process