Research Article

Treatment with Molgramostim (Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor, Rhugm-Csf, Mielogen) and Lenograstim (Granulocyte-Colony Stimulating Factor) Improves Experimental Colitis in Rats

Table 1

Experimental TNBS colitis in 62 male Wistar rats treated with CSF, GM-CSF and prednizolone, divided into 9 groups according to our experimental protocol.

GroupNumber of animals with TNBS colitisDay of euthanasiaTreatment with CSF (started)Treatment with rHu GSF (started)Treatment with prednisolone (started)

110 (control group, no treatment)15th
210 (control group, no treatment)30th
3619thImmediate treatment
4619th7 days after induction of colitis
5619th14 days after induction of colitis
6619thImmediate treatment
7619th7 days after induction of colitis
8614 days after induction of colitis
9615thImmediate treatment