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| Methods | Advantages | Disadvantages | Indicated patients |
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Conservative management | Topical antiperspirants | (i) Noninvasive (ii) Easy to use | (i) Temporary effects (ii) Poor efficacy | Mild to moderate AO patients |
| Botulinum toxin injection | (i) Good efficacy (ii) Noninvasive | (i) Need periodic use to maintain the efficacy (ii) Pain during the injection (iii) High cost | |
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Invasive management (to remove the apocrine glands) | Direct excision of dermis and subcutaneous tissues ± skin excision | (i) Good efficacy (ii) Under local anaesthesia | (i) Large wound (ii) Discomforts during postoperative periods (iii) Higher rates of hematoma formation, skin necrosis, keloid formation, and wound infection | Moderate to severe AO patients |
| Curettage | (i) Moderate to good efficacy (ii) Smaller wound and less painful than direct excision (iii) Under local anaesthesia | (i) Complications depend on the physician experience | |
Ultrasonic liposuction | (i) Moderate to good efficacy (ii) Small incision wound (iii) Short recovery time (iv) Under local anaesthesia | (i) Complications depend on the physician experience |
Laser-assisted | (i) Moderate to good efficacy (ii) Small incision wound (iii) Short recovery time (iv) Under local anaesthesia | (i) Higher recurrence rate than liposuction and surgery (ii) Higher complication incidence than the liposuction and surgery |
Microwave-based | (i) Good efficacy (ii) No surgical wound (iii) Short learning curve (iv) Under local anaesthesia | (i) Require multiple sessions to achieve better results (ii) Postoperative pain, swelling, and numbness (could be temporary) (iii) Possibility to injure the brachial nerve (iv) High cost |
Suction-assisted cartilage shaver | (i) Good efficacy (ii) Under local anaesthesia (iii) Better removal of the apocrine glands | (i) Long learning curve (ii) Complications depend on the physician experience |
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Sympathectomy | Upper thoracic sympathectomy | (i) Moderate to good efficacy | (i) Need general anaesthesia (ii) Compensatory hyperhidrosis (iii) Possibility of nerve injury (iv) Risk of pneumohemothorax |
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