FcgRIII Deficiency and FcgRIIb Deficiency Promote Renal Injury in Diabetic Mice

Figure 7

Relationship among FcgRI, FcgRIIb and FcgRIII in GMCs under the conditions of high glucose and oxLDL-IC. GMCs were cultured with normal glucose (5 mmol/l), high glucose (25 mmol/l), oxLDL-IC, or high glucose combined with oxLDL- IC. The mRNA expressions of FcgRIII (a), FcgRIIb (b) and FcgRI (c) were measured by real-time PCR. Data are expressed as the mean ± S.E. p < 0.05 versus NG; p < 0.05 versus HG + oxLDL- IC + siRNA-FcgRIIb.

(a)

(b)

(c)