The Effect of Carbogen Breathing on ¹⁸F-FDG Uptake in Non-Small-Cell Lung Cancer

Figure 3

Immunohistochemical visualization of hypoxia in A549 subcutaneous xenograft by pimonidazole and GLUT-1 staining under carbogen breathing condition. (a) Hypoxia detected by pimonidazole binding (green). (b) Hypoxia detected by GLUT-1 (red). (c) Overlay imaging shows little pimonidazole binding (green) with GLUT-1 overexpression. Scale bars = 0.2 mm. A total of 6 tumors were examined.

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