The Effect of Carbogen Breathing on ¹⁸F-FDG Uptake in Non-Small-Cell Lung Cancer

Figure 2

Immunohistochemical visualization of hypoxia in A549 subcutaneous xenografts by Pimonidazole and GLUT-1 staining under room air breathing condition. (a) Hypoxia detected by pimonidazole binding (green). (b) Hypoxia detected by GLUT-1 (red). (c) Overlay imaging shows that pimonidazole binding (green) and GLUT-1 expression (red) are generally colocalized. Both scale bars = 0.2 mm; a total of 10 tumors were examined.

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