Up-Regulated MicroRNA-27b Promotes Adipocyte Differentiation via Induction of Acyl-CoA Thioesterase 2 Expression

Figure 1

miR-27b increases lipid accumulation and adipocyte differentiation. (a) Oil red O staining of 3T3-L1 cells after adipocyte differentiation. At day 0 and day 3, control-miR (left panel) and miR-27b (right panel) were transfected into 3T3-L1 cells. Representative data from three different images are shown. Scale bars: 100 μm. (b) Intracellularly TG contents of control-miR and miR-27b transfected 3T3-L1 cells were measured. Each column represents the mean ± SEM from 6 independent experiments. ^∗Significantly difference than control-miR by Student’s t-test (). (c) Numbers of control-miR or miR-27b-transfected 3T3-L1 cells after adipocyte differentiation. Each column represents the mean ± SEM from 3 independent experiments.

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