Downregulating Serine Hydroxymethyltransferase 2 Deteriorates Hepatic Ischemia-Reperfusion Injury through ROS/JNK/P53 Signaling in Mice

Figure 1

Expression of SHMT2 after IR injury in mice. (a) The expression of SHMT2 was measured by western blot analysis at 4 h, 8 h, 16 h, 24 h, and 48 h after IR. (b) Quantification of SHMT2 levels in WB. Values represent the mean ± SD of at least three independent experiments. (c) SHMT2 detected in representative sections by immunofluorescence (IF) at 24 h and 48 h after IR (magnification: 400x). (d) Quantification of SHMT2-positive cells in stained sections (). (e) SHMT2 detected in representative sections by IHC at 24 h and 48 h after IR (magnification: ×400). (f) Quantification of SHMT2-positive cells in stained sections (). Values represent the mean ± SD of at least three independent experiments.