Association Study of the Caspase Gene Family and Psoriasis Vulgaris Susceptibility in Northeastern China

Table 8

Haplotype analysis of SNPs on the same chromosome for samples under 40 years old.

chr	SNP	Haplotype	Ca-freq	N-Ca ( 439)	Co-freq	N-Co (216)	P
1	rs4233532	CC	0.545	239.255	0.051	11.016	0.00000
	rs1052576	CT	0.401	176.039	0.338	73.008
		TC	0.054	23.706	0.611	131.976
11	rs506601	ACCCG	0.042	18.438	0.019	4.104	0.00098
	rs547584	ACCTA	0.119	52.241	0.105	22.68
	rs672016	ACGTA	0.035	15.365	0.024	5.184
		ATCCA	0	0	0.019	4.104
	rs507879	ATCCG	0.027	11.853	0.058	12.528
	rs2282659	ATCTA	0.309	135.651	0.224	48.384
		ATCTG	0.015	6.585	0.038	8.208
		ATGCG	0.053	23.267	0.043	9.288
		ATGTA	0.117	51.363	0.172	37.152
		TTCCG	0.026	11.414	0.054	11.664
		TTCTA	0.227	99.653	0.229	49.464
		TTCTG	0.018	7.902	0	0
		TTGTA	0.012	5.268	0.015	3.24
10	rs17090911	AC	0.094	41.266	0.102	22.032	0.08798
	rs2227310	GC	0.436	191.404	0.518	111.888
		GG	0.47	206.33	0.38	82.08
2	rs12613347	CACT	0	0	0.015	3.24	0.00000
	rs13006529	CATT	0.176	77.264	0.187	40.392
	rs6704688	CTCC	0	0	0.161	34.776
	rs2293554	CTCG	0.198	86.922	0	0
		CTCT	0.289	126.871	0.294	63.504
		CTTT	0	0	0.028	6.048
		TTCC	0	0	0.073	15.768
		TTCG	0.075	32.925	0	0
		TTCT	0.262	115.018	0.226	48.816
		TTTT	0	0	0.016	3.456
4	rs2705897	CGC	0.176	77.264	0.107	23.112	0.00001
	rs4647610	CGT	0	0	0.011	2.376
	rs5030545	CTC	0.183	80.337	0.182	39.312
		CTT	0.533	233.987	0.644	139.104
		TGC	0	0	0.02	4.32
		TTC	0.014	6.146	0.016	3.456
		TTT	0.094	41.266	0.02	4.32

Chr, Chromosome; SNP, single nucleotide polymorphism; N-Ca, number of case group; Ca-freq, case group frequencies; N-Co, Number of control group; Co-freq, control group frequencies; P, p value.