Association Study of the Caspase Gene Family and Psoriasis Vulgaris Susceptibility in Northeastern China

Table 6

The haplotype analyses result of CASPs in cases and controls.

Gene	Haplotype	Freq.	Case, Control Ratio Counts	Case, Control Frequencies	Chi Square	P Value
CASP3	TT	0.646	341.8  : 198.2, 401.9  : 210.1	0.633, 0.657	0.712	0.3989
	TC	0.177	94.2  : 445.8, 110.1  : 501.9	0.174, 0.180	0.057	0.8118
	GC	0.166	99.8  : 440.2, 90.9  : 521.1	0.185, 0.149	2.721	0.099
	GT	0.012	4.2  : 535.8, 9.1  : 602.9	0.008, 0.015	1.234	0.2666
CASP4	TC	0.632	334.5  : 205.5, 393.5  : 218.5	0.619, 0.643	0.685	0.408
	TG	0.201	109.5  : 430.5, 122.5  : 489.5	0.203, 0.200	0.013	0.911
	CC	0.143	82.5  : 457.5, 82.5  : 529.5	0.153, 0.135	0.758	0.384
	CG	0.023	13.5  : 526.5, 13.5  : 598.5	0.025, 0.022	0.106	0.7446
CASP7	GC	0.51	255.0  : 285.0, 333.0  : 279.0	0.472, 0.544	5.934	0.0149
	GG	0.407	234.0  : 306.0, 235.0  : 377.0	0.433, 0.384	2.894	0.0889
	AC	0.082	51.0  : 489.0, 44.0  : 568.0	0.094, 0.072	1.928	0.165
CASP8	CT	0.546	304.0  : 236.0, 325.2  : 286.8	0.563, 0.531	1.157	0.282
	TT	0.222	117.0  : 423.0, 138.8  : 473.2	0.217, 0.227	0.172	0.6787
	CG	0.214	111.0  : 429.0, 135.8  : 476.2	0.205, 0.222	0.457	0.4991
	TG	0.018	8.0  : 532.0, 12.2  : 599.8	0.015, 0.020	0.43	0.5121
CASP9	TC	0.582	314.9  : 225.1, 355.9  : 256.1	0.583, 0.582	0.003	0.9559
	CT	0.365	198.9  : 341.1, 221.9  : 390.1	0.368, 0.363	0.041	0.8397
	CC	0.05	26.1  : 513.9, 31.1  : 580.9	0.048, 0.051	0.037	0.8465
CASP10	CT	0.431	232.3  : 307.7, 264.4  : 347.6	0.430, 0.432	0.004	0.9506
	TT	0.353	191.7  : 348.3, 214.6  : 397.4	0.355, 0.351	0.023	0.8783
	CA	0.215	114.7  : 425.3, 132.6  : 479.4	0.212, 0.217	0.031	0.8596

: significant; Freq.: frequencies.