Longitudinal Changes of PAI-1, MMP-2, and VEGF in Peritoneal Effluents and Their Associations with Peritoneal Small-Solute Transfer Rate in New Peritoneal Dialysis Patients

Table 1

Baseline characteristics of peritoneal dialysis patients (n = 70).

Variables	Mean	SD
Age (years)	56.4	±13.4
PD vintage (months)	2.1	±1.5
Gender, Male (n, %)	35	50.0%
Diabetes mellitus (n, %)	33	47.1%
ACEi/ARB (n, %)	7	10.0%
Statin (n, %)	30	42.9%
Laboratory measurements
hemoglobin(g/dL)	10.4	±1.5
albumin (g/dL)	3.6	±0.4
fasting glucose(mg/dl)	106	93-198
PET measurements
Category
high transport	14	20.3%
high average transport	23	33.3%
low average transport	22	31.9%
low transport	10	14.5%
Total KtV	2.1	±0.5
Residual Renal Ccr (ml/min/1.73m^2)	34.9	14.4-53.6
Total Ccr (ml/min/1.73m^2)	73.3	56.8-86.3
nPCR(g/day)	1.1	±0.3

Paired test p-value is estimated using paired t-test.
PD, peritoneal dialysis; ACEi, angiotensin converting enzyme inhibitor; ARB, angiotensin receptor blockade; VEGF, vascular endothelial growth factor; PAI-1, plasminogen activator inhibitor-1; MMP2, matrix metalloproteinases 2; D/P Cr, dialysate: plasma creatinine.