Tumor Suppressive Function of NQO1 in Cutaneous Squamous Cell Carcinoma (SCC) Cells

Figure 5

Effect of NQO1 on the intracellular signaling molecules. After adenoviral transduction, cells were cultured for 2 d. Overexpression of NQO1 decreased the level of phosphorylated AKT, JNK, and p38 MAPK, whereas knockdown of NQO1 increased the level of those signaling molecules.