Insulin Resistance and Cardiovascular Risks in Different Groups of Hemodialysis Patients: A Multicenter Study
Table 2
Odd ratios of having traditional cardiovascular risks among hemodialysis patients with insulin resistance.
High SBP
High DBP
High TC
High LDL-C
Low HDL-C
High TG
IFG
OR (95%CI)
OR (95%CI)
OR (95%CI)
OR (95%CI)
OR (95%CI)
OR (95%CI)
OR (95%CI)
Normal weight
Model 1
0.42 (0.20, 0.86)
0.90 (0.50, 1.63)
0.80 (0.38, 1.68)
0.83 (0.49, 1.39)
1.68 (0.99, 2.86)
2.79 (1.54, 5.06)
8.22 (4.35, 15.52)
Model 2
0.36 (0.17, 0.76)
1.13 (0.60, 2.12)
0.81 (0.37, 1.75)
0.78 (0.45, 1.36)
1.75 (1.01, 3.06)
3.41 (1.78, 6.53)
8.15 (4.14, 16.02)
Overweight/Obese
Model 1
1.68 (0.71, 3.97)
1.05 (0.51, 2.19)
1.14 (0.52, 2.50)
0.84 (0.45, 1.58)
3.65 (1.58, 8.45)
2.90 (1.50, 5.61)
6.06 (2.33, 15.74)
Model 2
1.69 (0.66, 4.29)
0.75 (0.33, 1.68)
0.99 (0.42, 2.33)
0.80 (0.41, 1.55)
4.15 (1.71, 10.06)
3.06 (1.53, 6.13)
10.76 (3.36, 34.5)
Non-diabetes
Model 1
0.69 (0.37, 1.31)
1.15 (0.63, 2.07)
0.78 (0.39, 1.56)
0.90 (0.54, 1.51)
2.38 (1.39, 4.07)
3.40 (1.85, 6.25)
10.64 (5.78, 19.58)
Model 2
0.61 (0.31, 1.18)
1.21 (0.64, 2.30)
0.64 (0.31, 1.35)
0.76 (0.44, 1.33)
2.14 (1.23, 3.75)
3.22 (1.69, 6.12)
12.54 (6.39, 24.63)
Diabetes
Model 1
1.49 (0.54, 4.15)
0.93 (0.45, 1.93)
1.00 (0.43, 2.32)
0.77 (0.41, 1.45)
2.40 (1.07, 5.38)
3.75 (1.91, 7.37)
Model 2
2.11 (0.70, 6.31)
0.94 (0.43, 2.05)
1.16 (0.44, 3.05)
0.78 (0.40, 1.54)
3.07 (1.28, 7.33)
4.29 (2.05, 8.98)
Overall
Model 1
0.80 (0.47, 1.37)
1.00 (0.63, 1.58)
0.80 (0.47, 1.37)
0.72 (0.48, 1.07)
2.65 (1.71, 4.11)
3.67 (2.39, 5.66)
8.14 (4.77, 13.89)
Model 2
0.76 (0.43, 1.32)
1.11 (0.68, 1.83)
0.75 (0.42, 1.32)
0.63 (0.41, 0.96)
2.53 (1.59, 4.01)
3.58 (2.25, 5.69)
7.99 (4.50, 14.18)
Significant level at p < 0.05, p < 0.01, and p < 0.001. Model 1: elevated HOMA-IR and traditional CVD risk factors. Model 2: adjusted for age, gender, hemodialysis vintage, Charlson comorbidity index, physical activity, and body mass index (for nondiabetes, diabetes, and overall sample). SBP, systolic blood pressure; DBP, diastolic blood pressure; TC, total cholesterol; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; TG, triglyceride; IFG, impaired fasting glucose.
