Research Article
Plasma and Renal Cortex Meropenem Concentrations in Patients Undergoing Percutaneous Renal Biopsy
Table 2
Meropenem concentration in patients.
| | | eGFR (mL/min/1.73 m2) | 1st blood sample (T1) | 2nd blood sample (T2) | 3rd blood sample (T3) | Kidney sample | | Concentration (µg/mL) | Time (min) | Concentration (μg/mL) | Time (min) | Concentration (μg/mL) | Time (min) | Concentration (μg/mL) |
| | P. 1 | 22 | 42.1 | 80 | 20.6 | 150 | 19.3 | 50 | 4.5 | | P. 2 | 11 | 58.8 | 95 | 39.6 | 135 | 26.6 | 80 | 4.1 | | P. 3 | 127 | 44.6 | 95 | 4.6 | 150 | 6.9 | 60 | 4.5 | | P. 4 | 17 | 60.0 | 80 | 43.4 | 175 | 45.0 | 70 | 1.8 | | P. 5 | 21 | 35.9 | 60 | 21.9 | 135 | 9.6 | 50 | 1.3 | | P. 6 | 117 | 47.1 | 80 | 9.4 | 150 | 3.7 | 70 | 1.0 | | P. 7 | 39 | 43.3 | 100 | 29.1 | 160 | 25.5 | 80 | 6.0 | | P. 8 | 90 | 32.2 | 65 | 8.8 | 135 | 4.9 | 75 | 1.6 | | P. 9 | 45 | 46.6 | 60 | 19.9 | 95 | 12.7 | 50 | 7.0 | | P. 10 | 124 | 27.8 | 100 | 8.0 | 210 | 3.8 | 85 | 0.4 | | P. 11 | 96 | 41.8 | 100 | 9.9 | 165 | 4.7 | 90 | 1.7 | | P. 12 | 34 | 54.5 | 75 | 26.2 | 95 | 32.3 | 65 | 3.2 | | P. 13 | 7 | 57.1 | 40 | 34.0 | 190 | 26.4 | 30 | 1.9 | | P. 14 | 58 | 50.6 | 120 | 14.6 | 150 | 11.3 | 110 | 3.9 | | Mean | 57.5 (±44.1) | 45.9 (±9.8) | 82.1 (±21.2) | 20.7 (±12.9) | 149.6 (±31.5) | 16.6 (±12.8) | 68.9 (±20.3) | 3.1 (±2.0) |
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Time after finalized meropenem infusion (T1). eGFR: estimated glomerular filtration rate with CKD-EPI and P: patient. |
