Research Article
Different Membrane Pathways Mediate Ca2+ Influx in Adrenal Chromaffin Cells Exposed to 150–400 ns Electric Pulses
Table 1
Effect of blocking VGCCs on 150 ns pulse-induced increases in
.
| VGCC blocker | Relative fluorescence intensity | Reduction in amplitude (%) | - test ( value) | Control | VGCC blocked |
| ω-Agatoxin GVIA (100 nM) | | | 24 | | ω-Conotoxin (20 nM) | | | 9 | NS | Nimodipine (5 μM) | | | 0 | | Nitrendipine (5 μM) | | | 0 | | | | | 48 | | Nimodipine (20 μM) | | | 53 | | Nitrendipine (20 μM) | | | 62 | | | | | 67 | |
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Nitrendipine at 5 μM; nitrendipine at 20 μM; NS: not significant. |