Research Article
Mammographic Breast Density and Breast Cancer Molecular Subtypes: The Kenyan-African Aspect
Table 1
Select characteristics of breast cancer patients with pretreatment diagnostic mammograms, Aga Khan University Hospital, Kenya, 2014-2015.
| Clinical characteristic | Overall () | ER-positive | ER-negative | | (%) | | (%) | | (%) |
| Age | | | | | | | <50 years | 48 | 39 | 37 | 41 | 11 | 33 | ≥50 years | 75 | 61 | 53 | 59 | 22 | 67 | Mean (years), SD | 54 (11) | 53 (11) | 57 (12) | Median (range) | 54 (27-83) | 54 (27-81) | 54 (39-83) | Menopausal status | | | | | | | Pre | 42 | 34 | 33 | 37 | 9 | 27 | Post | 81 | 66 | 57 | 63 | 24 | 73 | BMI category | | | | | | | Lean | 18 | 15 | 13 | 14 | 5 | 15 | Overweight | 54 | 44 | 40 | 44 | 14 | 42 | Obese | 43 | 35 | 32 | 36 | 11 | 33 | Missing | 8 | 7 | 5 | 6 | 3 | 9 | Mean (kg/m2), SD | 29 (4.8) | 29 (4.7) | 28 (5.3) | Median (range) | 28 (18-46.8) | 28 (19-45.6) | 28 (18-46.8) | Diagnosis | | | | | | | Invasive ductal | 105 | 85 | 77 | 86 | 28 | 85 | Other | 18 | 15 | 13 | 14 | 5 | 15 | Tumor size | | | | | | | <3 cm | 53 | 43 | 44 | 49 | 9 | 27 | ≥3 cm | 58 | 47 | 39 | 43 | 19 | 58 | Missing | 12 | 10 | 7 | 8 | 5 | 15 | Mean (cm), SD | 3.3 (1.8) | 3.3 (1.8) | 3.4 (1.9) | Median (range) | 3 (0.5-10) | 2.7 (1-10) | 3 (0.5-8) | Tumor grade | | | | | | | Grade 1 | 14 | 11 | 13 | 14 | 1 | 3 | Grade 2 | 57 | 46 | 51 | 57 | 6 | 18 | Grade 3 | 49 | 40 | 25 | 28 | 24 | 73 | Missing | 3 | 2 | 1 | 1 | 2 | 6 | Nodal status | | | | | | | Negative | 49 | 40 | 36 | 40 | 13 | 39 | Positive | 60 | 49 | 46 | 51 | 14 | 42 | Missing | 14 | 11 | 8 | 9 | 6 | 18 | PR status | | | | | | | Negative | 40 | 33 | 9 | 10 | 31 | 94 | Positive | 83 | 67 | 81 | 90 | 2 | 6 | HER2 status | | | | | | | Negative | 94 | 76 | 71 | 79 | 23 | 70 | Positive | 22 | 18 | 14 | 16 | 8 | 24 | Equivocal/DCIS | 7 | 6 | 5 | 6 | 2 | 6 | TNBC status | | | | | | | Negative | 95 | 77 | 85 | 94 | 10 | 30 | Positive | 21 | 17 | 0 | 0 | 21 | 64 | Missing | 7 | 6 | 5 | 6 | 2 | 6 |
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BMI: body mass index; ER: estrogen receptor; HER2: human epidermal growth factor receptor 2; PR: progesterone receptor; TNBC: triple negative breast cancer.
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