Hypoxia Imaging and Biological Evaluation of the Radiosensitizing Effect of Oleanolic Acid

Figure 2

Enhanced antitumor effects of irradiation combined with OA. (a) Kaplan-Meier analysis of the survival of the tumor-bearing rats in the four groups. Sixty days after tumor cells inoculated into rats, survival rates of tumor-bearing rats in the control group, OA group, IR group, and OA combined with IR group were 0, 0, 16.7%, and 33.3%, respectively. (b) Tumor growth curve. Tumor volumes were inhibited in the IR group and OA combined with IR group; however, there was no significant difference between them.

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