Review Article
Cisplatin-Induced Rodent Model of Kidney Injury: Characteristics and Challenges
Table 9
Surface markers of inflammatory cells in cisplatin rodent model.
| Surface marker | Inflammatory cells that express surface marker | Ref. |
| CD45+ | pan-leukocyte marker | [162] |
| CD19+ (CD79α) | marker of B cells | [163] |
| CD3+ | marker of T cells | [163] |
| F4/80+ | canonical marker of macrophages, monocytes | [73] |
| CD11c+ | canonical marker of DC, recently also macrophages, activated CD8+ T cells, plasma B cell blasts, NK | [66, 73, 164] |
| CD14+ | monocytes, macrophages, dendritic cells, neutrophils | [165] |
| CD11b+ | macrophages, monocytes, neutrophils, dendritic cells | [73] |
| CD11b+CD27+ | NK (immature, mature) | [166] |
| CD49b+ | pan-NK marker, small subset of CD8+ T cells, platelets | [68] |
| F4/80+CD11c-CD206+ | macrophages M2 | [167] |
| F4/80+CD11c+ | macrophages M1 | [167] |
| F4/80-CD11c+ | dendritic cells | [167] |
| GR-1+ | neutrophils, monocytes | [73] |
| GR-1+ CD11b+ CD11c+ | monocyte-derived proinflammatory DC | [73] |
| GR-1+ CD11b+ CD11c- | neutrophils, monocytes | [73] |
| 7/4+ | monocytes, neutrophils | [73] |
| Ly6G+ | neutrophils | [73] |
| 7/4+Ly6G- | monocytes | [73] |
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DC: dendritic cells; NK: natural killer cells
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