The Interaction of Selectins and PSGL-1 as a Key Component in Thrombus Formation and Cancer Progression

Figure 2

Ratio of vessels occluded with thrombi after collagen-epinephrine challenge in PSGL-1 knockout (filled bars) and wild-type (open bars) mice. A significantly reduced rate of thrombus formation was observed in knockout animals both with Masson trichrome staining and with an immunohistochemical staining to mouse fibrin (reprinted from Thrombosis Research with permission by Elsevier).