Red Cell Distribution Width Is Associated with All-Cause and Cardiovascular Mortality in Patients with Diabetes

Table 3

Association between RDW and all-cause and cardiovascular mortality.

	All-cause mortality		CV mortality
	HR (95% CI)	value	HR (95% CI)	value
Unadjusted
versus	1.54 [1.19–1.98]	0.001	1.64 [1.02–2.65]	0.041
versus	1.79 [1.40–2.29]	<0.001	2.16 [1.37–3.41]	0.001
versus	3.44 [2.74–4.32]	<0.001	3.34 [2.16–5.17]	<0.001
Per 1%	1.20 [1.16–1.23]	<0.001	1.15 [1.08–1.23]	<0.001
Model
versus	1.20 [0.93–1.55]	0.16	1.25 [0.77–2.02]	0.37
versus	1.35 [1.05–1.74]	0.02	1.57 [0.99–2.50]	0.058
versus	2.37 [1.85–3.03]	<0.001	2.22 [1.39–3.55]	0.001
Per 1%	1.16 [1.11–1.20]	<0.001	1.10 [1.01–1.19]	0.032
Model
versus	1.17 [0.89–1.54]	0.27	1.23 [0.74–2.06]	0.43
versus	1.25 [0.94–1.65]	0.12	1.37 [0.81–2.32]	0.24
versus	2.03 [1.54–2.68]	<0.001	1.96 [1.16–3.31]	0.012
Per 1%	1.14 [1.09–1.20]	<0.001	1.09 [0.98–1.20]	0.13
Model 3^ǂ
versus	1.26 [0.68–2.35]	0.47	1.30 [0.78–2.19]	0.32
versus	1.66 [0.91–3.04]	0.098	1.41 [0.83–2.38]	0.21
versus	2.39 [1.30–4.38]	0.005	1.99 [1.17–3.37]	0.011
Per 1%	1.09 [0.99–1.22]	0.094	1.08 [0.97–1.20]	0.15

1: age, gender, race, and hemoglobin. 2: Model 1 + HF, MI, stroke, malignancy, CKD, BMI, SBP, and cholesterol. ^ǂModel 3: Model 2 + oral antidiabetics, insulin, statins, ACE/ARBs, and diuretics.