Research Article
Prevalence and Clinical Characteristics of Itch in Vitiligo and Its Clinical Significance
Table 1
Demographic data and clinical characteristics of vitiligo patients with and without itch.
| Characteristics | Itch | Nonitch | |
| Age, mean ± SD (years) | 46.5 ± 16.0 | 45.2 ± 16.2 | 0.519 |
| Gender, (%) | | | 0.601 | (i) Male | 27 (33.3) | 117 (36.4) | | (ii) Female | 54 (66.7) | 204 (63.6) | |
| Onset (years), median (range) | 37 (0–72) | 36 (1–75) | 0.438 |
| Duration of vitiligo (years), median (range) | 6 (0–59) | 7 (0.83–51) | 0.456 |
| Family history of vitiligo, (%) | 17 (21.0) | 73 (22.7) | 0.735 |
| Family history of thyroid and autoimmune disease, (%) | 10 (12.4) | 40 (12.5) | 0.978 |
| Leukotrichia, (%) | 38 (46.9) | 151 (47.0) | 0.984 |
| Body surface area involvement (%), median (range) | 3 (0.2–50) | 2 (0.1–90) | 0.458 |
| Fitzpatrick skin types, (%) | | | 0.521 | (i) Type III | 13 (16.0) | 57 (17.8) | | (ii) Type IV | 57 (70.4) | 234 (72.9) | | (iii) Type V | 11 (13.6) | 30 (9.3) | |
| Type of vitiligo, (%) | | | 0.618 | (i) Nonsegmental | 63 (77.8) | 258 (80.4) | | (ii) Segmental | 13 (16.0) | 51 (15.9) | | (iii) Focal | 5 (6.2) | 12 (3.7) | |
| Initial location, (%) | | | | (i) Head and neck | 37 (45.7) | 143 (44.6) | 0.855 | (ii) Trunk | 13 (16.1) | 17 (5.3) | 0.001 | (iii) Arms | 4 (4.9) | 38 (11.8) | 0.070 | (iv) Hands | 17 (21.0) | 103 (32.1) | 0.051 | (v) Legs | 9 (11.1) | 23 (7.2) | 0.241 | (vi) Feet | 5 (6.2) | 12 (3.7) | 0.354 |
| Associated diseases, (%) | 28 (34.6) | 110 (34.3) | 0.959 | (i) Hyperthyroidism | 1 (2.6) | 15 (9.6) | 0.560 | (ii) Hypothyroidism | 1 (2.6) | 11 (6.7) | 0.560 | (iii) Diabetes mellitus | 3 (3.7) | 14 (4.4) | 1.000 | (iv) Allergic rhinitis/asthma | 6 (7.4) | 22 (6.9) | 0.861 | (v) Alopecia areata | 1 (1.2) | 9 (2.8) | 0.368 | (vi) Halo nevi | 3 (3.7) | 19 (5.9) | 0.319 |
| Positive results for anti-microsomal antibody | 16 (25.4) | 75 (30.0) | 0.472 | Positive results for anti-thyroglobulin antibody | 12 (19.5) | 49 (19.8) | 0.888 | Positive results for ANA | 30 (45.5) | 117 (45.2) | 0.967 |
| TSH level | | | 0.216 | (i) Low | 2 (3.23) | 16 (7.31) | | (ii) Normal | 60 (96.77) | 195 (89.04) | | (iii) High | 0 (0) | 8 (3.65) | |
| DLQI, median (range) | 7 (0–26) | 5 (0–26) | 0.001 |
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