Development of a Murine Infection Model with Leishmania killicki, Responsible for Cutaneous Leishmaniosis in Algeria: Application in Pharmacology

Table 1

Detection of L. major and L. killicki DNA and parasitesin various tissues of BALB/c mice. ND, not determined.

Leishmania	Tissue or organ	PCR after inoculation/LIT culture
		2 weeks	4 weeks	8 weeks	12 weeks	16 weeks	20 weeks
L. major	Ear (inoculation site)	+	+	+	+/ND
	Draining lymph node	+	+	+	+/+
	Spleen	+	+	+	+/+
	Liver	−	+	+	+/+
L. killicki	Ear (inoculation site)	+	+	+	+/ND	+	+
	Draining lymph node	−	+	+	+/+	+	+
	Spleen	−	+	+	+/+	+	+
	Liver	−	+	+	+/+	ND	ND